Cytokeratins Biosensing Using Tilted Fiber Gratings

Cytokeratins Biosensing Using Tilted Fiber Gratings

Blog Article

Optical fiber gratings have widely proven their applicability in biosensing, especially when they are coupled with antibodies for specific antigen recognition.While this is customarily done with fibers coated by a thin metal film to benefit from plasmonic enhancement, in this paper, we propose to study their intrinsic properties, developing a label-free sensor for the detection of biomarkers SEJARAH PENGUASAAN SUMBER DAYA PESISIR DAN LAUT DI TELUK TOMINI in real-time without metal coatings for surface plasmon resonances.We focus on the inner properties of our modal sensor by immobilizing receptors directly on the silica surface, and reporting the sensitivity of bare tilted fiber Bragg gratings (TFBGs) used Carcass detection and consumption by facultative scavengers in forest ecosystem highlights the value of their ecosystem services at near infrared wavelengths.We test different strategies to build our sensing surface against cytokeratins and show that the most reliable functionalization method is the electrostatic adsorption of antibodies on the fiber, allowing a limit of detection reaching 14 pM by following the guided cladding modes near the cut-off area.These results present the biodetection performance that TFBGs bring through their modal properties for different functionalizations and data processing strategies.